Registration: NCT04788953
Status: Registered
Tags: Medication, Trial registration, Wake‑promoting
External URL: https://clinicaltrials.gov/study/NCT04788953
This clinical trial is studying whether solriamfetol, a wake-promoting medication, can help reduce excessive sleepiness in people working early-morning shifts. Participants take either solriamfetol or a placebo, and researchers measure changes in alertness, performance, and overall daily function. The study remains in the recruiting phase with no published results yet.
Early-morning and overnight schedules often leave workers fighting sleepiness right when they need to be most alert. Solriamfetol is designed to boost wakefulness signals in the brain, which could make it easier to stay focused and safe on the job. If the trial confirms its benefits, it may become another option for managing shift-work-related sleepiness, alongside healthy scheduling and light-based strategies.
Shift‑work sleepiness focus.