Registration: PMCID: PMC11181222
Status: Published
Tags: Cardiometabolic, Occupational health, Systematic review
External URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC11181222/
This systematic review analyzed 15 studies published between 2013 and 2023 on shift work and coronary artery disease (CAD). Most studies assessed risk, with one looking at management. Overall, shift workers were found to have a higher risk of CAD compared to non-shift workers. Longer duration of shift work was linked with greater risk, and some studies showed more coronary artery plaques in workers with many years of night or rotating shifts. The review notes that while the exact biological mechanisms are not fully clear, circadian rhythm disruption, stress, and metabolic changes are thought to contribute. The authors conclude that evidence is strong enough to support creating occupational guidelines to reduce CAD risk in shift workers.
For people working nights or rotating shifts, this review reinforces that irregular schedules can take a toll on heart health. The longer someone spends in shift work, the more their risk of coronary artery disease may rise. While the exact “why” is still being studied, factors like disrupted sleep, stress, and metabolic strain are likely involved. This matters because it frames shift work not just as a scheduling challenge but as a long-term health issue — making heart health an important area of focus for both workers and employers.
Open access (Cureus).