Night‑Shift Work, Genetic Risk, and Type 2 Diabetes in the UK Biobank

Night‑Shift Work, Genetic Risk, and Type 2 Diabetes in the UK Biobank

Type: Prospective cohort study

Registration: PMCID: PMC5860836

Status: Published

Tags: Cardiometabolic, Cohort, Diabetes, General population

External URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC5860836/

Summary

Night‑shift work—especially rotating—was associated with higher odds of type 2 diabetes; shift exposure did not modify polygenic risk.

Why It Matters For Night Shift Workers and Night Owls

Prospective data how timing of light, sleep, meals, and schedules tracked with sleep, alertness, recovery, and metabolic markers for night‑shift workers and night owls. Overall, the data make the schedule itself visible in physiology, not just in how people feel subjectively. For the audience living on night schedules, the key meaning is that the schedule’s timing choices show up in measurable outcomes.

Tags

  • Cardiometabolic
  • Cohort
  • Diabetes
  • General population

Notes

Large UK Biobank analysis.

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