Type: Randomized controlled trial
Registration: PMCID: PMC2584099
Status: Published
Tags: Melatonin, Nurses, RCT, Sleep
External URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC2584099/
Compared 5 mg melatonin vs placebo after night shifts; melatonin improved some sleep outcomes in shift‑working nurses.
Participants randomized in this trial whether melatonin timed before daytime sleep showed sleep & alertness for night‑shift workers and night owls. Results help move melatonin from vague sedative to a time‑sensitive tool studied in the context of night schedules. For people who work nights, that frames an everyday choice (when you eat, how you light the end of a shift, how rest is split) as part of the mechanism, not just routine.
Open access RCT in nurses.