Armodafinil for Treatment of Excessive Sleepiness Associated with Chronic Shift Work Disorder

Armodafinil for Treatment of Excessive Sleepiness Associated with Chronic Shift Work Disorder

Type: Randomized controlled trial

Registration: PMCID: PMC2770907

Status: Published

Tags: Armodafinil, Night-shift workers, RCT, Shift Work Disorder (SWD), Sleep

External URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC2770907/

Summary

12‑week, multi‑center RCT found armodafinil significantly improved wakefulness during scheduled night work and overall clinical condition vs placebo.

Why It Matters For Night Shift Workers and Night Owls

This RCT whether keeping most calories in a daytime window, with minimal overnight intake, showed sleep & alertness for night‑shift workers and night owls. The signal puts timing—rather than only calories or macros—at the center of how bodies respond to working at night. For people who work nights, that frames an everyday choice (when you eat, how you light the end of a shift, how rest is split) as part of the mechanism, not just routine.

Tags

  • Armodafinil
  • Night-shift workers
  • RCT
  • Shift Work Disorder (SWD)
  • Sleep

Notes

PubMed: https://pubmed.ncbi.nlm.nih.gov/19880686/

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