Type: Randomized controlled trial
Registration: Nature Communications article
Status: Published
Tags: Cardiometabolic, Chrononutrition, General population, RCT
External URL: https://www.nature.com/articles/s41467-025-57846-y
Keeping meals to daytime during simulated night work mitigated adverse changes in cardiovascular risk factors vs eating at night.
Participants randomized in this trial whether keeping most calories in a daytime window, with minimal overnight intake, showed sleep, alertness, recovery, and metabolic markers for night‑shift workers and night owls. The signal puts timing—rather than only calories or macros—at the center of how bodies respond to working at night. For people who work nights, that frames an everyday choice (when you eat, how you light the end of a shift, how rest is split) as part of the mechanism, not just routine.
Press summaries: NIH/NHLBI, Harvard Sleep Medicine.