Lemborexant in Shift‑Work Insomnia

Lemborexant in Shift‑Work Insomnia

Registration: NCT05344443

Status: Registered

Tags: Insomnia, Medication, Trial registration

External URL: https://clinicaltrials.gov/study/NCT05344443

Summary

This clinical trial is testing whether a sleep medication called lemborexant can help night-shift workers who have trouble sleeping during the day. Participants first go through a two-week observation period, then take either lemborexant or a placebo for two weeks. The main goal is to see if the medication helps them sleep longer and better after working night shifts. The study is still in the recruiting phase, and no results have been published yet.

Why It Matters For Night Shift Workers and Night Owls

Sleeping during the day after a night shift is one of the hardest challenges for shift workers. Even when they’re tired, the body’s natural signals often keep them awake. Lemborexant works by calming those wake-promoting signals, which may allow for deeper, longer rest. If the trial confirms its benefits, this medication could become another option for shift workers dealing with persistent insomnia when schedule changes or lifestyle adjustments aren’t enough.

Tags

  • Insomnia
  • Medication
  • Trial registration

Notes

DORAs for sleep on nights.

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