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How Sleep–Wake Triggers Shape Rest

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How Sleep–Wake Triggers Shape Rest

Circadian health expert and medical scientist Logan Pendergrast, Ph.D., explains the two core processes that regulate the sleep–wake cycle: the homeostatic sleep drive and circadian rhythm. The homeostatic sleep drive functions like a pressure gauge, with adenosine building throughout the day to increase sleepiness and then resetting during sleep. Alongside this, the circadian rhythm acts as the body’s internal clock, aligning hormone release, metabolism, and energy levels with the demands of daily life.
The segment also addresses how social cues—such as meal timing, work schedules, and social interactions—interact with these systems. For shift workers, these cues can easily disrupt the balance between circadian rhythm and sleep pressure, leading to desynchronization and reduced wellbeing. Dr. Pendergrast highlights how understanding these triggers can help individuals make adjustments that support healthier sleep patterns and overall function.

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