Sleep Science Foundations
Sleep is more than just rest, it’s a structured cycle that impacts everything from physical recovery to memory and mood. In this video, Logan Pendergrast, Ph.D. breaks down the fundamentals of how sleep works, including the four main stages, the role of REM and deep sleep, and practical ways to improve sleep quality. Ideal for anyone curious about how to sleep better, especially those navigating late nights or unusual schedules.
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hello everyone and welcome to night
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owling my name is Logan and I am here
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today to talk to you about sleep in this
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lesson we'll talk about sleep in general
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what sleep is how it breaks down we'll
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talk a bit about some of the health
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benefits of sleep maybe how to optimize
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our sleep itself and then we'll get into
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a bit of the downsides of what happens
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when we miss a night's
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sleep as a general overview what we'll
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first talk about is the mechanics of the
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sleep cycle what are the different
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periods of sleep within a given sleep
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cycle we'll then move into some of the
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core factors that are involved in sleep
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some of the factors that can help
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optimize um the performance of our sleep
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throughout the night we'll then get into
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the impact of sleep itself on our health
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and how missing out on maybe even a few
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hours of sleep can have detriments to
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our overall health and then lastly we
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will talk a bit about our personal
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assessment which is available on the
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night owling website and can help us get
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an idea of where we sit in terms of our
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general sleep
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hygiene so we will begin here with the
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mechanics of the sleep cycle itself
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so the way to think about sleep is that
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sleep is made up of various cycles
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multiple cycles within a given sleep
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interval so over the period of 8 hours
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there are about four to six cycles of
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sleep now within each cycle of sleep
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there are stages and as you can see in
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the figure above my head here each of
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these stages varies in terms of not only
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its name but in terms of how deep the
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sleep itself is and what actually occurs
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during this phase of sleep
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and generally the stages of sleep within
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a sleep cycle are characterized as
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either NRM or NREM which is nonrapid eye
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movement sleep or rapid eye movement
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sleep and rapid eye movement sleep is
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exactly what you think it is the eyes
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are closed but even though the eyes are
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closed themselves the eyes are darting
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around
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rapidly and what this is indicative of
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is not only the given stage within a
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given sleep cycle but also the activity
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that is going on neurologically during
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the given sleep cycle stage
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so next here we will get into the more
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specific aspects of the stages of sleep
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and beginning here first with the NREM
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stage one area of sleep now this area of
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sleep is considered to be a
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transitionary phase between being awake
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generally in our day-to-day lives and
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transitioning into sleep itself it
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typically lasts about 1 to 5 minutes and
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this is where we begin to experience
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drops in heart rate drops in our
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breathing rate just a general relaxation
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of the body but also it is during this
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phase where we experience what's called
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a hypnic jerk now hypnic is the Greek
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word for sleep it actually comes from
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the Greek word hypnos and a jerk is like
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a jerking sensation like an awake
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sensation and it's thought that this
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occurs actually because our body as
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we're beginning to relax and as the
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sleep process is initiating the brain
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wires get a bit confused and confuse the
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relaxation sensation with a falling
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sensation which is why sometimes it is
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during this phase of sleep that we begin
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to jerk awake or our partner maybe in
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the bed next to us jerks awake and then
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jerks us awake so this stage one sleep
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is considered to be like a transitionary
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phase and what it transitions into is
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what's called enrem stage two sleep now
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this enrem stage 2 sleep can last
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anywhere from about 20 to 25 minutes and
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it is during this phase where we start
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to see a slowing of brain activity and
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additionally we see a drop in core body
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temperature and now this drop in core
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body temperature is is relatively
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essential for a deepening of the sleep
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process and it can actually be
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facilitated by just dropping the
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temperature in the room as we go to
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sleep at night so maybe dropping the
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temperature in the room to 68 to 69° F
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can help facilitate um a a deeper sleep
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phase as we transition through the uh
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the various sleep stages
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now another phenomenon actually that
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happens during this stage two sleep is
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what's called sleep spindles and
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essentially the function of this during
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the stage 2 sleep is to dampen the
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brain's response to outside noises or
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outside phenomenon and you can kind of
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think of this as a burst of brain
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activity that turns on your brain's do
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not disturb mode
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essentially allowing you to relax more
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effectively so now we will move into
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talking about the deeper phases of sleep
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and the phase that we'll start with here
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is enrem stage three sleep now this
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phase of sleep is where we're getting
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into a bit of a deeper phase we see that
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sleep in this um stage lasts about 20 to
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40 minutes and during this stage we see
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increases in what's called growth
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hormone now this hormone is responsible
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for helping tissues of the body recover
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from exercise or from any sort of
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previous injury and it also is
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responsible for improvements in organ
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function and during this stage three
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sleep we can see this slowing of the
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brain activity which is tied to the
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general difficulty of waking up during
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this phase so if it's the case that we
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wake up during stage three sleep or even
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the next stage that I'm going to talk
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about stage four sleep the body feels
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generally a bit more groggy and it's a
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bit more unnatural to wake up during
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this stage of sleep so if the alarm goes
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off or something like that during this
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stage it it can be quite
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jarring and transitioning here and into
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this next phase this finally reaching
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this or rapid eye movement stage of
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sleep now stages 1 2 and three were
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non-rapid eye movement now we've finally
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reached rapid eye movement this stage of
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sleep is also about 20 to 40 minutes it
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is actually the stage of sleep where
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this growth hormone that helps us
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recover our organs and our muscles is at
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its
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highest and interestingly during this
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phase we see highly um active brain
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activity and it's actually quite similar
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to the wakeful period and although there
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are various theories of why we dream it
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is actually during this phase that we do
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dream and that we begin to kind of
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consolidate the emotions and experiences
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that we have seen throughout the
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previous day or in the past um
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noteworthy amount of
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time and we see that the generally
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during this phase as well that the
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muscles are in a stationary state
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they're you're almost kind of a bit
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paralyzed um physically during this
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stage of sleep although of course it's
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temporary and as I mentioned this brain
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activity actually during the phase of
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sleep facilitates memory consolidation
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or just generally making sure that we
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remember our memories and so this stage
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of sleep is quite effective for helping
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us improve our general brain activity
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and our general brain
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health and so this really brings us to
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the end of the explanation of the stages
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of sleep and as I mentioned here at the
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bottom of this slide uh I know that
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these stages can be grouped together
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quite often and perhaps a bit difficult
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to spread apart but really this
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information should serve to just help us
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understand what given stages occur
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within a sleep cycle and how these
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stages are relevant to the function of
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our bodies
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so now that we've spoken a bit about
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sleep stages and sleep cycles and the
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depth to which sleep can go we can now
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begin to talk a bit about the core
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factors that relate to our sleep and the
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first core factor that we'll speak about
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here is called circadian rhythm now that
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word circadian is actually a Latin word
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it breaks down into two separate Latin
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words circa meaning around and den
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meaning day so this word essentially
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just means your body's rhythm throughout
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the day and I guess night in this
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circumstance so one big factor that
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regulates our body's rhythm is actually
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light so we're by nature activated
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during the day we're moving during the
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day and because of that our eyes are
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actually sensitive to light and now in
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in nature that's sunlight of course but
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in our modern world this can also be
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screens can be overhead lighting and so
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this is why it's quite important
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actually to in the time right before
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we're getting ready to go to sleep maybe
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1 or 2 hours begin to avoid sources of
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light avoid staring closely at our cell
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phone for extended periods of time avoid
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watching television for extended periods
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of time and the reason for this is
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because if the body sees this external
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light it really doesn't know the
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difference between this external light
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and sunlight so it begins to think that
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it's daytime and will reduce your
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ability to go to sleep
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effectively and the way it reduces the
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way to go to sleep effectively is
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through a hormone that is called
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melatonin now mel melatonin is a hormone
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that's associated with sleep and what it
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does is prepares the body to relax and
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to drop its temperature so as to allow
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us to reach deeper phases of
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sleep and so because of melatonin it's
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actually also important to have a
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consistent sleep schedule to have a
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consistent within about half an hour to
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an hour time period of going to bed the
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same time every night and this allows
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the brain itself actually to know when
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to release melatonin in order to
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effectively prepare you for
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sleep now thinking next bit here more
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into preparing for sleep this gets us
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into what's called sleep pressure now
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sleep pressure is what it sounds like
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it's the amount of pressure you feel to
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be going to sleep throughout the day now
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it's less like peer pressure or external
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pressure and more of an internal
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pressure if you've ever been awake for
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20 or so hours you know what sleep
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pressure feels like it's essentially a
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buildup of a neurotransmitter called
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adenosine and this adenosine
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neurotransmitter that's in our brains is
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associated with increased amounts of
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tiredness it's actually the the
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neurotransmitter that caffeine helps
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impair the activity of so it's caffeine
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is essentially reducing adenosine
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activity and helping to at least delay
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feelings of sleepiness and it's not only
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actually the amount of time that we're
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awake that regulates our sleep pressure
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but it's also the activities that we're
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doing while we're awake this could be
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exercise extended periods of walking
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working perhaps or even social
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engagement all of these factors can help
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um or hinder our ability to feel the
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sleep uh pressure for engaging in a
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deeper phase of sleep as we move
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throughout our evening moving into the
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next core factors of sleep we begin to
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talk about our sleep environment this is
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the room that we are sleeping in so some
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of the factors as I've mentioned
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previously that are important for the
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improvement of a sleeping environment
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can be the darkness of the given room so
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as I mentioned in the previous slide our
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body actually thrives when we're
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sleeping in a dark environment and
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particularly a dark and a cool
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environment and so in this case it's
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effective to have blackout curtains and
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minimal light in the room so the body
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itself doesn't perceive that it's
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daytime
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it's also effective as I'd mentioned
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previously to have a cooler room perhaps
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dropping the uh thermostat temperature
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down to 68
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69° it's effective to have a quiet
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environment or to have an environment
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where the noise is predictable something
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like having a white noise or a fan
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playing can help so that any sort of
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other noises that are occurring outside
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of the room don't disrupt the sleep
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cycle
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itself and then as of course you would
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expect comfortable bedding bedding that
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is breathable and allows the body to
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move around comfortably is a an very
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important aspect for helping improve the
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general quality of sleep itself within
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the sleep
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environment now the next aspect of sleep
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that is considered to be core is our
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lifestyle and our habits so as I
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mentioned in the previous slide caffeine
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is a delaying factor when it comes to
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feeling tiredness however we actually
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want to feel tired as we're beginning to
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go to sleep that feeling of being tired
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is associated with that buildup of
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adenosine and the function of melatonin
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and it helps our body prepare physically
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to go into sleep so it's usually the
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case that we should avoid the
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consumption of caffeine prior to going
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to sleep so that our body can function
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effectively additionally alcohol
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consumption can interfere with the depth
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to which our body can go to sleep and
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without going into too much detail
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alcohol can actually stop our body from
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reaching the deeper phases of sleep such
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as phase 3 and phase 4
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sleep additionally it's quite helpful to
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engage in exercise throughout the day
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exercise can help the body generally
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feel a bit more sleep pressure and help
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the body generally function a bit more
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uh effectively from a blood flow
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perspective eating habits are also quite
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important for preparing our body for
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sleep uh it's the case actually that if
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we eat too large of a meal within about
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2 hours of going to sleep that our body
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temperature elevates in order to digest
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the food effectively and it stops our
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body from reaching deeper phases of
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sleep because as I've mentioned
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previously the body temperature actually
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needs to drop in order to reach these
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stage three and stage four areas of
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sleep and then stress management
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although in many cases of course stress
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is out of our control um having a
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generally stressfree life or a low
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stress life can help us generally fall
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asleep more effectively and then that
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carries into our general sleep hygiene
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itself and then the last bit here maybe
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a bit um that is out of our control in
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some circumstances but still worth
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noting for those of us with sleep
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disorders such as sleep insomnia or
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sleep apnea it can be quite difficult to
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effectively sleep so it is in these
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circumstances that we should seek to
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talk to our doctors our health care
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professionals to help us manage the
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quality of our sleep more effectively
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and although this ties in with the
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stress management factor from the the
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previous bullets generally anxiety and
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depression can also be one of some of
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these factors that we should talk to our
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healthcare provider about helping um to
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alleviate so that we can allow our
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bodies to engage in more restful sleep
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uh age as well is a factor so as we
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reach uh later ages I won't name the
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actual ages themselves but the body has
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a less effective means of reaching
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deeper phases of sleep uh and this can
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cause problems with memory consolidation
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etc and m much of this is essentially
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out of the control of the individual
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it's just part of the aging process but
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what it does is it makes it more
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important than ever as we reach the
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later age years of our life to
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prioritize sleep and prioritize
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effective sleep and then lastly here
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recently there have been discoveries to
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say that there is a genetic factor to
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our ability to sleep there's a genetic
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factor that relates to us being kind of
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early birds people who are comfortable
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waking up in the morning that's me or
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being night owls which are those of us
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who are just more having more fun or
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functioning better during the evening
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and so some individuals are just
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genetically awake at a later time and of
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course these are individuals who should
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be considering that avoidance of light
16:52
as they reach their sleeping time is
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very uh important because those of us
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who are early birds we just kind of go
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to sleep when the sun goes down but it
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is those night owls who will need to
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seek to avoid these external sources of
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light such as cell phones and screens
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before reaching the sleep
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period now we will move into talking
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about the impacts of sleep on our health
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and in particular the impacts of our
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sleep on our health in the short term so
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beginning first with brain function as I
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mentioned previously sleep is highly
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integrated with the function of our
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brains we see that individuals with
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healthy sleep hygiene and who have slept
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well in the previous night have improved
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focus general memory function and also
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reaction time in fact speaking of
17:38
reaction time the uh deprivation of
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sleep affects cognitive function in a
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way that is similar to alcohol
17:47
intoxication
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and so many of these uh studies I think
17:51
have been performed in surgeons and you
17:54
can see that a diminishment of sleep
17:58
quality in surgeons leads to more
18:00
mistakes in the operating room so it's
18:02
quite important to have proper sleep
18:05
hygiene not only for our general memory
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consolidation in the way that we feel
18:10
but also in our performance in our
18:12
occupation sleep as well uh affects the
18:15
immune system we see that individuals
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with proper sleep behaviors have
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elevated function in resistance to
18:22
illness in fact individuals who sleep
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less than 6 hours per night are actually
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four times more likely to um get a cold
18:31
um and experience other illnesses so the
18:33
sleep uh is highly integrated within the
18:36
immune function in the body and then
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additionally what we see is that sleep
18:40
is highly regulating mood function which
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may not come as a surprise to many of
18:45
you after a night of poor sleep we don't
18:47
actually feel the best emotionally but
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sleep helps us regulate our anxiety and
18:52
our emotional stability which itself
18:54
feeds into our sleep function in the
18:57
long term moving now into our health in
19:00
the long term we actually see that
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health is highly affected in terms of
19:06
our risk of chronic disease by healthy
19:08
sleep so reductions in heart disease
19:12
diabetes and blood pressure are seen in
19:14
individuals who experience elevated
19:17
sleep quality over long periods of time
19:20
we see that these individuals also
19:22
experience healthy weight in a generally
19:24
robust metabolism and part of the reason
19:26
that this is the case is that sleep is
19:28
highly integrated with our hunger
19:30
hormones and our hunger hormones thereby
19:33
lead to us eating are seeking of food
19:37
behaviors and we actually see that
19:39
individuals who are deprived of sleep
19:42
see an increased cravings for high
19:44
calorie foods by about 50% meaning poor
19:48
sleep means poor effects on the hunger
19:52
and satiety or food seeking hormones and
19:56
thereby a disruption in our ability to
19:58
manage our weight
20:00
effectively and then as usual sleep
20:03
health goes to brain health and brain
20:06
health is affected by elevated quality
20:09
of sleep over long periods of time by a
20:11
reduction in dementia an improvement in
20:13
general emotional well-being and an
20:16
enhancement in our long-term memory and
20:18
in fact good sleep boosts the recall of
20:22
memory by up to 40% meaning that sleep
20:25
overall is not just healthy for our
20:27
brains but also healthy for our ability
20:30
to function and resist chronic diseases
20:33
but also manage our body
20:36
weight so now to finalize this
20:38
presentation we will just talk about a
20:40
bit of the information that we've
20:41
covered over this past 20 minutes we can
20:44
remember from the beginning of this talk
20:46
that sleep stages occur over the course
20:49
of a night we actually have sleep cycles
20:51
which are made up of sleep stages those
20:53
sleep stages vary in terms of not only
20:56
how long they last but also how deep the
20:58
sleep is and the functions that happen
21:00
within the body in a given amount of
21:02
time over sleep we see that there are
21:05
factors such as our circadian rhythm
21:07
which regulate our body's preparedness
21:09
to go to sleep and to function and sleep
21:12
effectively and we also see that
21:14
deprivation of our quality of sleep can
21:17
lead to impairments in our general
21:19
memory function but also it can weaken
21:22
our immune system and lead to us
21:23
becoming sick more easily and then also
21:26
we see increases in stress and impacts
21:29
in our ability to regulate our food
21:31
seeking behaviors which could impair our
21:33
ability to manage our body weight
21:36
however improvements in the sleep
21:38
quality can improve our general memory
21:40
and our brain function also improve our
21:43
immune system and then as well help with
21:46
elevating our mood and our ability to
21:48
reduce our risk of chronic disease such
21:49
as heart disease and
21:51
dementia and so with that all of this
21:54
information in mind thank you for
21:56
attending and thank you for listening
21:58
and we will talk to you at the next talk